ASSOCIATE PROFESSOR AT THE DEPARTMENT OF GENERAL NURSING OF NURSING SCHOOL OF RIBEIRÃO PRETO/UNIVERSITY OF SAO PAULO (USP).
Integrative Physiology focusing on neuroendocrine control of inflammation response.
1989 Bachelor Degree – Nursing at Nursing School of Ribeirão Preto-University of São Paulo.
1992 Master degree – Medical Physiology at School of Medicine of Ribeirão Preto-University of São Paulo, Brazil. Supervisor: Dr. Wamberto A. Varanda.
1997 Ph.D. – Medical Physiology, at School of Medicine of Ribeirão Preto University of São Paulo University of São Paulo, Brazil. Supervisors: Dr. José Antunes Rodrigues /Dr. Jolanta Gutkowska (University of Montreal-Canada).
2008-2009 – Post-doctoral Fellow-Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary, Alberta, Canada. Supervisor: Dr. Quentim Pittman.
1997-2002 Assistant Professor at Nursing School at University of São Paulo, Brazil.
2002-2017 Associate Professor at Nursing School at Univesrity of São Paulo.
WHAT WE DO
Our lab has several research interests and employs multiple approaches to investigate neuroendocrine function in animals submmited to systemic inflammation. We benefit from numerous collaborations with colleagues in nearby laboratories.
We are interested in the mechanisms related to the pathophysiology of inflammatory diseases, so we use animal models of septic shock to explore the participation of neuro endocrine mediators in this model of pathology.
We have developed studies focused on the regulation of blood pressure, as well as on body temperature and cytokine production in animals during this pathophysiology situation.
We also carry out studies with culture of peritoneal macrophages where they are stimulated with bacterial products and evaluate its function against different hormonal modulators.
• Marcelo Eduardo Batalhão
• Aline Jesus
• Andre Luiz Tomaz de Souza
• Carlitos Singolani Junior
• Felipe Faim
• Patricia Passaglia
1. Differential Role of Neurohypophysial Hormones in Hypotension and Nitric Oxide Production During Endotoxaemia. Stabile AM, Moreto V, Batalhão ME, Rocha MJ, Antunes-Rodrigues J, Cárnio EC. J Neuroendocrinol. 2016 Jun;28(6).
2. Cholecystokinin inhibits inducible nitric oxide synthase expression by lipopolysaccharide-stimulated peritoneal macrophages. Saia RS, Mestriner FL, Bertozi G, Cunha FQ, Cárnio EC. Mediators Inflamm. 2014;2014:896029.
3. Cardiovascular and inflammatory response to cholecystokinin during endotoxemic shock. Saia RS, Bertozi G, Mestriner FL, Antunes-Rodrigues J, Queiróz Cunha F, Cárnio EC. Shock. 2013 Jan;39(1):104-13.
4. Role of dexamethasone on vasopressin release during endotoxemic shock. Batalhão ME, Moreto V, Stabile AM, Antunes-Rodrigues J, Carnio EC. Regul Pept. 2008 Apr 10;147(1-3):67-71.
5. Hypothermia during endotoxemic shock in female mice lacking inducible nitric oxide synthase. Saia RS, Anselmo-Franci JA, Carnio EC. Shock. 2008 Jan;29(1):119-26.
6. Neuro-immune-endocrine mechanisms during septic shock: role for nitric oxide in vasopressin and oxytocin release. Carnio EC, Moreto V, Giusti-Paiva A, Antunes-Rodrigues J. Endocr Metab Immune Disord Drug Targets. 2006 Jun;6(2):137-42.
7. Inducible nitric oxide synthase pathway in the central nervous system and vasopressin release during experimental septic shock. Giusti-Paiva A, De Castro M, Antunes-Rodrigues J, Carnio EC. Crit Care Med. 2002 Jun;30(6):1306-10.